David Cameron came a cropper when he took to the airwaves to trumpet the latest economic growth figures.
During an interview with BBC Tees, the Prime Minister annoyed presenter Lisa McCormick by repeatedly referring to examples of how the economy was flourishing on Tyneside.
"You keep mentioning the River Tyne," she finally snapped. "That's not our region Prime Minister. I'm sorry, we are the River Tees."
A flustered Mr Cameron replied: "I'm sorry, I thought I was doing...." before going on hastily to point out that the Government was investing £90 million in the Tees Valley.
But that did nothing to placate Ms McCormick who pointed out that it was pouring £470 million into Greater Manchester and £440 million into the South East.
"Ninety million pounds seems like a drop in the ocean to me," she said.
It is not the first time Mr Cameron has appeared not to know where he was while doing a local radio interview.
During a BBC Essex interview in Colchester earlier this year, he had to apologise after appeared to suggest he was in neighbouring Chelmsford.
Tom Blenkinsop, Labour MP for Middlesbrough South and East Cleveland said Mr Cameron is "out of touch" and disinterested in Teesside.
He said: "Over the last four years of David Cameron we've had a Tory peer calling the region 'desolate', frequent misspellings of Teesside in official Number 10 letters and now the Prime Minister himself can't even take the basic cue of appearing on BBC Tees to get the hint that our river is the Tees and not the Tyne.
"This just highlights how David Cameron is out of touch with the region and completely disinterested in places like Middlesbrough, Stockton, Redcar, Hartlepool and East Cleveland."